This book encompasses the theoretical and practical aspects of surgical ethics, with a focus on the application of ethical standards to everyday surgical practice and the resolution of ethical conflicts in the surgical arena. It provides surgeons in the different surgical fields with deep, practical insights into the topic. A 21st century surgeon requires complete competence as well as solid ethical values. Ethics are placed at the core of surgical professionalism, so surgeons must be not only proficient and expert but (...) also ethically and morally reliable. Surgical decision-making can be considered as a two-step process: the “how to treat” aspect is a matter of surgical science, while “why to treat” issues are a matter of surgical ethics and are based on ethical principles. As such, every surgeon should have a moral compass to guide his or her actions, always placing the welfare and rights of the patients above their own. The book provides invaluable background and insights for solving the ethical conflicts surgeons around the globe encounter in their daily practice. Each chapter will also include features such as key point summaries in the beginning of the chapters, explanatory boxes, a glossary and suggested readings. Surgical Ethics - Principles and Practice is an authoritative work in the field designed for experienced surgeons, surgical residents, and fellows, all of whom are confronted with ethics issues and conflicts in practice. (shrink)

Coll sees in the Christian worldview three core values that can be used to discern moral political actions: the importance of history, the ubiquity of tragedy, and practical wisdom.

Coll clearly advocates the Aristotelian notion that "moral principles are ultimately realized only in specific acts which human beings choose to carry out." He cites Washington, Lincoln, and Churchill as examples of leaders whose moral wisdom in political reasoning led to a statecraft explicitly derived from prudence.

A statesman's responsibility to act morally while remaining politically fastidious is a primary difficulty in international relations. Theories that provide definitive guidance for political morality are often viewed with suspicion and considered unrealistic. Coll, in opposition to this dismissive approach, sees in the Christian worldview three core values that can be used to discern moral political actions: the importance of history, the ubiquity of tragedy, and practical wisdom. Coll explicates the Christian tradition that informs each of these values and considers (...) their pertinence in international relations today. He goes on to extract some general prescriptions for foreign policy, showing that these core values speak to military action, immigration, foreign aid, and the environment. (shrink)

Alternative splicing (AS) greatly expands the coding capacities of genomes by allowing the generation of multiple mature mRNAs from a limited number of genes. Although the massive switch in AS profiles that often accompanies variations in gene expression patterns occurring during cell differentiation has been characterized for a variety of models, their causes and mechanisms remain largely unknown. Here, we integrate foundational and recent studies indicating the AS switches that govern the processes of cell fate determination. We include some distinct (...) AS events in pluripotent cells and somatic reprogramming and discuss new progresses on alternative isoform expression in adipogenesis, myogenic differentiation and stimulation of immune cells. Finally, we cover novel insights on AS mechanisms during neuronal differentiation, paying special attention to the role of chromatin structure. (shrink)

Experimental philosophy was an exciting and extraordinarily successful development in the study of nature in the seventeenth century. Yet experimental philosophy was not without its critics and was far from the only natural philosophical method on the scene. In particular, experimental philosophy was contrasted with and set against speculative philosophy and, in some quarters, was accused of tending to irreligion. This volume brings together ten scholars of early modern philosophy, history and science in order to shed new light on the (...) complex relations between experiment, speculation and religion in early modern Europe. The first six chapters of the book focus on the respective roles of experimental and speculative philosophy in individual seventeenth-century philosophers. They include Francis Bacon, Robert Boyle, Margaret Cavendish, Thomas Hobbes, John Locke and Isaac Newton. The next two chapters deal with the relation between experimental philosophy and religion with a special focus on hypotheses and natural religion. The penultimate chapter takes a broader European perspective and examines the paucity of concerns with religion among Italian natural philosophers of the period. Finally, the concluding chapter draws all these individuals and themes together to provide a critical appraisal of recent scholarship on experimental philosophy. (shrink)

The emergence of experimental philosophy was one of the most significant developments in the early modern period. However, it is often overlooked in modern scholarship, despite being associated with leading figures such as Francis Bacon, Robert Boyle, Isaac Newton, Jean Le Rond d'Alembert, David Hume and Christian Wolff. Ranging from the early Royal Society of London in the seventeenth century to the uptake of experimental philosophy in Paris and Berlin in the eighteenth, this book provides new terms of reference for (...) understanding early modern philosophy and science, and its eventual eclipse in the shadow of post-Kantian notions of empiricism and rationalism. Experimental Philosophy and the Origins of Empiricism is an integrated history of early modern experimental philosophy which challenges the rationalism and empiricism historiography that has dominated Anglophone history of philosophy for more than a century. (shrink)

In the mid-seventeenth century a movement of self-styled experimental philosophers emerged in Britain. Originating in the discipline of natural philosophy amongst Fellows of the fledgling Royal Society of London, it soon spread to medicine and by the eighteenth century had impacted moral and political philosophy and even aesthetics. Early modern experimental philosophers gave epistemic priority to observation and experiment over theorising and speculation. They decried the use of hypotheses and system-building without recourse to experiment and, in some quarters, developed a (...) philosophy of experiment. The movement spread to the Netherlands and France in the early eighteenth century and later impacted Germany. Its important role in early modern philosophy was subsequently eclipsed by the widespread adoption of the Kantian historiography of modern philosophy, which emphasised the distinction between rationalism and empiricism and had no place for the historical phenomenon of early modern experimental philosophy. The re-emergence of interest in early modern experimental philosophy roughly coincided with the development of contemporary x-phi and there are some important similarities between the two. (shrink)

La característica central del pensamiento filosófico del siglo XX (si más no, de la llamada a día de hoy 'filosofía analítica') ha sido el interés por el estudio del lenguaje. El lenguaje religioso no ha sido una excepción a este interés. Uno de los ejemplos más tempranos de esta preocupación por el estudio del lenguaje religioso es el análisis propuesto por R. B. Braithwaite en su "An Empiricist's View of the Nature of Religious Belief" (1955). Dicho muy brevemente, la idea (...) básica de Braithwaite es que el lenguaje religioso no describe el mundo: aquellos que realizan una afirmación de índole religiosa no están aceptando la verdad de una proposición sino que están simplemente expresando su compromiso con un determinado código de conducta. Es por ello, dice Braithwaite, que adoptar una creencia religiosa no consiste en aceptar que el mundo se corresponde con una descripción de hechos determinada, sino en comprometerse a actuar de acuerdo con un código de conducta. El objetivo de este artículo es ofrecer un análisis crítico de la propuesta de Braithwaite. (shrink)

This volume has 41 chapters written to honor the 100th birthday of Mario Bunge. It celebrates the work of this influential Argentine/Canadian physicist and philosopher. Contributions show the value of Bunge’s science-informed philosophy and his systematic approach to philosophical problems. The chapters explore the exceptionally wide spectrum of Bunge’s contributions to: metaphysics, methodology and philosophy of science, philosophy of mathematics, philosophy of physics, philosophy of psychology, philosophy of social science, philosophy of biology, philosophy of technology, moral philosophy, social and political (...) philosophy, medical philosophy, and education. The contributors include scholars from 16 countries. Bunge combines ontological realism with epistemological fallibilism. He believes that science provides the best and most warranted knowledge of the natural and social world, and that such knowledge is the only sound basis for moral decision making and social and political reform. Bunge argues for the unity of knowledge. In his eyes, science and philosophy constitute a fruitful and necessary partnership. Readers will discover the wisdom of this approach and will gain insight into the utility of cross-disciplinary scholarship. This anthology will appeal to researchers, students, and teachers in philosophy of science, social science, and liberal education programmes. 1. Introduction Section I. An Academic Vocation Section II. Philosophy Section III. Physics and Philosophy of Physics Section IV. Cognitive Science and Philosophy of Mind Section V. Sociology and Social Theory Section VI. Ethics and Political Philosophy Section VII. Biology and Philosophy of Biology Section VIII. Mathematics Section IX. Education Section X. Varia Section XI. Bibliography. (shrink)

Background Consent policies for post-mortem organ procurement (OP) vary throughout Europe, and yet no studies have empirically evaluated the ethical implications of contrasting consent models. To fill this gap, we introduce a novel indicator of governance quality based on the ideal of informed support, and examine national differences on this measure through a quantitative survey of OP policy informedness and preferences in seven European countries. -/- Methods Between 2017–2019, we conducted a convenience sample survey of students (n = 2006) in (...) Austria (AT), Belgium (BE), Denmark (DK), Germany (DE), Greece (GR), Slovenia (SI) and Spain (ES), asking participants about their donation preferences, as well as their beliefs and views about the policy in place. From these measures, we computed indices of informedness, policy support, and fulfilment of unexpressed preferences, which we compared across countries and consent systems. -/- Results Our study introduces a tool for analyzing policy governance in the context of OP. Wide variation in policy awareness was observed: Most respondents in DK, DE, AT and BE correctly identified the policy in place, while those in SI, GR and ES did not. Respondents in opt-out countries (AT, BE, ES and GR) tended to support the policy in place (with one exception, i.e., SI), whereas those in opt-in countries (DE and DK) overwhelmingly opposed it. These results reveal stark differences in governance quality across countries and consent policies: We found a preponderance of informed opposition in opt-in countries and a general tendency towards support–either informed or uninformed–in opt-out countries. We also found informed divergence in opt-in countries and a tendency for convergence–either informed or uninformed–among opt-out countries. -/- Conclusion Our study offers a novel tool for analyzing governance quality and illustrates, in the context of OP, how the strengths and weaknesses of different policy implementations can be estimated and compared using quantitative survey data. (shrink)

Physical activity, and likely the motivation for it, varies throughout the day. The aim of this investigation was to create a short assessment (CRAVE: Cravings for Rest and Volitional Energy Expenditure) to measure motivation states (wants, desires, urges) for physical activity and sedentary behaviors. Five studies were conducted to develop and evaluate the construct validity and reliability of the scale, with 1,035 participants completing the scale a total of 1,697 times. In Study 1, 402 university students completed a questionnaire inquiring (...) about the want or desire to perform behaviors “at the present moment (right now).” Items related to physical activity (e.g., “move my body”) and sedentary behaviors (e.g., “do nothing active”). An exploratory structural equation model (ESEM) revealed that 10 items should be retained, loading onto two factors (5 each for Move and Rest). In Study 2, an independent sample (n= 444) confirmed these results and found that Move and Rest desires were associated with stage-of-change for exercise behavior. In Study 3, 127 community-residing participants completed the CRAVE at 6-month intervals over two years- two times each session. Across-session interclass correlations (ICC) for Move (ICC = 0.72–0.95) and Rest (ICC = 0.69–0.88) were higher than when they were measured across 24-months (Move: ICC = 0.53; Rest: ICC = 0.49), indicating wants/desires have state-like qualities. In Study 4, a maximal treadmill test was completed by 21 university students. The CRAVE was completed immediately pre and post. Move desires decreased 26% and Rest increased 74%. Changes in Move and Rest desires were moderately associated with changes in perceived physical fatigue and energy. In Study 5, 41 university students sat quietly during a 50-min lecture. They completed the CRAVE at 3 time points. Move increased 19.6% and Rest decreased 16.7%. Small correlations were detected between move and both perceived energy and tiredness, but not calmness or tension. In conclusion, the CRAVE scale has good psychometric properties. These data also support tenets of the WANT model of motivation states for movement and rest (Stults-Kolehmainen et al., 2020a). Future studies need to explore how desires to move/rest relate to dynamic changes in physical activity and sedentarism. (shrink)

Neste texto, os três professores que presidiram até hoje a Comissão Brasileira de Filosofia Medieval fazem um histórico da mesma, salientando 0s encontros e congressos realizados, as publicações feitas e os projetos para o futuro.

Papers of the international conference "Franz von Baader: Philosophie und Theologie im Spannungsfeld von Technik, Naturwissenschaft und Geschichte" held Oct. 3-6, 2013 in Dresden.

This book builds on the idea that pragmatics and philosophy are strictly interconnected and that advances in one area will generate consequential advantages in the other area. The first part of the book, entitled ‘Theoretical Approaches to Philosophy of Language’, contains contributions by philosophers of language on connectives, intensional contexts, demonstratives, subsententials, and implicit indirect reports. The second part, ‘Pragmatics in Discourse’, presents contributions that are more empirically based or of a more applicative nature and that deal with the pragmatics (...) of discourse, argumentation, pragmatics and law, and context. The book presents perspectives which, generally, make most of the Gricean idea of the centrality of a speaker’s intention in attribution of meaning to utterances, whether one is interested in the level of sentence-like units or larger chunks of discourse. (shrink)

We report on the small-scale (0.5 13 h - 1M, a large-scale bias of ~2.0 and a satellite fraction of 12 ± 2 per cent. Thus, these galaxies occupy haloes with average masses in between those of the higher redshift BOSS CMASS sample and the original SDSS I/II luminous red galaxy sample © 2012 The Authors Published by Oxford University Press on behalf of the Royal Astronomical Society © doi:10.1093/mnras/sts314.

This note makes a contribution to the issue raised in a paper by Popper and Miller (1983) in which it was claimed that probabilistic support is purely deductive. Developing R. C. Jeffrey's remarks, a new general approach to the crucial concept of "going beyond" is here proposed. By means of it a quantitative measure of the inductive component of a probabilistic inference is reached. This proposal leads to vindicating the view that typical predictive probabilistic inferences by enumeration and analogy are (...) purely inductive. (shrink)

The association of resilience-related factors with frailty is a recent research topic. Dispositional optimism and context sensitivity are two psychological factors that differently contribute to individual resilience. This study aimed at investigating whether dispositional optimism and context sensitivity might contribute to a multifactorial model of frailty, together with established relevant factors such as cognitive and physical factors. This cross-sectional study involved 141 elderly outpatients aged ≥65 years, who were referred to the Geriatrics and Multidimensional Evaluation Clinic of the University Hospital (...) of Messina. We used the following measures: the Mini-Mental State Examination to screen for global cognitive functioning; 4-m gait speed and handgrip strength to measure physical performance; a 35-item Frailty Index to evaluate patients’ frailty status; the revised Life Orientation Test to gauge dispositional optimism; and the Context Sensitivity Index to measure context sensitivity. We found that LOT-R, CSI, and MMSE were all significantly associated with FI. Gait speed was only marginally associated with FI. The present study showed a novel association of dispositional optimism and context sensitivity with frailty among elderly outpatients. These preliminary findings support a multidimensional approach to frailty in which even peculiar psychological features might provide a significant contribution. (shrink)

We study the SIS and SIRI epidemic models discussing different approaches to compute the thresholds that determine the appearance of an epidemic disease. The stochastic SIS model is a well known mathematical model, studied in several contexts. Here, we present recursively derivations of the dynamic equations for all the moments and we derive the stationary states of the state variables using the moment closure method. We observe that the steady states give a good approximation of the quasi-stationary states of the (...) SIS model. We present the relation between the SIS stochastic model and the contact process introducing creation and annihilation operators. For the spatial stochastic epidemic reinfection model SIRI, where susceptibles S can become infected I, then recover and remain only partial immune against reinfection R, we present the phase transition lines using the mean field and the pair approximation for the moments. We use a scaling argument that allow us to determine analytically an explicit formula for the phase transition lines in pair approximation. (shrink)

George Edward Moore.--Bertrand Russell.--Ludwig Wittgenstein.--Moritz Schlick.--Hans Reichenbach.--Rudolf Carnap.--Karl R. Popper.--Gilbert Ryle.--Willard Van Orman Quine.

Entre 1991 e 2000, a porcentagem de católicos caiu de 83,3% para 73,9%, a dos evangélicos cresceu de 9% para 15,6% e a dos “sem religião” subiu de 4,7% para 7,4%. Como entender essas mudanças? Qual a responsabilidade da Igreja católica? O artigo apresenta, primeiramente, a visão sobre a diversidade religiosa, as mudanças ocorridas nas últimas décadas. Discute a seguir sobre a “Força e fraqueza da presença católica”, construindo um “mapa do catolicismo”. O terceiro enfoque reflete sobre as causas desse (...) “enfraquecimento”, especialmente, os movimentos migratórios da população brasileira e os problemas da resposta da Igreja para acompanhar essa mudança, tanto nas “novas frentes migratórias” quanto nas periferias dos grandes centros. Deixando o campo católico, analisa-se a diversidade das igrejas evangélicas ou os protestantes tradicionais e depois a “expansão pentecostal”, em sua enorme diversidade, com destaque ao neopentecostalismo e seu profissionalismo empresarial. Finalmente, aborda-se o fenômeno das “outras religiões” e o crescimento dos “sem-religião”. Palabras clave: Religião; Diversidade religiosa; Panorama religioso brasileiro; Censo 2000; Igreja católica. ABSTRACT Between 1991 and 2000, the percentage of catholics dropped from 83,3% to 73,9%, that o the evangelicalsgrew from 9% to 15,6%, and that of people ‘without a religion’ rose from 4,7% to 7,4%. How can we understand those changes? How far is the Catholic church responsible? This article starts with a view of religious diversity and the changes that took place in the last decades. It then goes on to discuss the ‘power and weakness of the Catholic presence’, drawing a ‘map of Catholicism’. O terceiro The third part focuses on the causes of that ‘weakening’, mainly the migratory flows of the Brazilian population and the problems of the church response to those changes, in the ‘new migratory fronts’ as well as in the periphery of big urban centres. Beyond the Catholic scope, it analyses the diversity of evangelical churches r traditional protestants, and then ‘pentecostal expansion’, in its enormous diversity, with emphasis on neopentecostalism and its entrepreneurial professionalism. Finally, it considers the phenomenon of ‘other religions’ and the growing number of those ‘without a religion’. Key words: Religion; Religious diversity; Brazilian religious panorama; 2000 Census; Catholic Church. (shrink)

The transition semantics presented in Rumberg (J Log Lang Inf 25(1):77–108, 2016a) constitutes a fine-grained framework for modeling the interrelation of modality and time in branching time structures. In that framework, sentences of the transition language L_t are evaluated on transition structures at pairs consisting of a moment and a set of transitions. In this paper, we provide a class of first-order definable Kripke structures that preserves L_t-validity w.r.t. transition structures. As a consequence, for a certain fragment of L_t, validity (...) w.r.t. transition structures turns out to be axiomatizable. The result is then extended to the entire language L_t by means of a quite natural ‘Henkin move’, i.e. by relaxing the notion of validity to bundled structures. (shrink)

Hempel's high probability requirement asserts that any rationally acceptable answer to the question 'Why did event X occur?' must offer information which shows that X was to be expected at least with reasonable probability. Salmon rejected this requirement in his S-R model. This led to a series of paradoxical consequences, such as the assertion that an explanation of an event can both lower its probability and make it arbitrarily low, and the assertion that the explanation of an outcome would have (...) qualified as an explanation of its non-occurrence as well. We argue that if inductive explanations are to be seen as generalizations of the causal-deterministic model, or if they are to be seen as satisfying the requirement--fulfilled by the D-N model--that explanations ought to identify certain features of the universe that are nomically responsible for the explanadum event, then the high probability requirement seems to be unacceptable. If this is so, a realistically inspired theory of inductive explanation will be committed to the paradoxes that follow from Salmon's model. (shrink)

The transition semantics presented in Rumberg :77–108, 2016a) constitutes a fine-grained framework for modeling the interrelation of modality and time in branching time structures. In that framework, sentences of the transition language \ are evaluated on transition structures at pairs consisting of a moment and a set of transitions. In this paper, we provide a class of first-order definable Kripke structures that preserves \-validity w.r.t. transition structures. As a consequence, for a certain fragment of \, validity w.r.t. transition structures turns (...) out to be axiomatizable. The result is then extended to the entire language \ by means of a quite natural ‘Henkin move’, i.e. by relaxing the notion of validity to bundled structures. (shrink)

Alberto Cortes, in [1], attempts to show that Leibniz's Principle of The Identity of Indiscernibles is a principle restricted to individuals, and that photons appear to violate L. L is stated by Leibniz as “no two substances are completely similar, or differ solo numero.” In second-order quantification theory with identity L becomes.